published scientific reports

This section is published for health professionals. Here we share some of the hundreds of published research studies that have been carried out on sulforaphane and chlorophyll and wheatgrass juice.

Sulforaphane Science

Research topics include:

Cancer & Carcinogens: Sulforaphane

Intestinal Health: Sulforaphane

Autism: Sulforaphane

Alzheimer’s Disease: Sulforaphane

Parkinson’s Disease: Sulforaphane

Skin Disorders: Sulforaphane

Aging: Sulforaphane

Eyes: Sulforaphane

Air Pollution: Sulforaphane

Diseases caused by Protein Misfolding: Sulforaphane

Wheatgrass and Chlorophyll Science

Research topics include:

Cancer: Chlorophyll

Chronic Disease: Chlorophyll

Increases Haemoglobin in Blood: Chlorophyll

Reduces Symptoms of Hayfever: Chlorophyll

Sulforaphane Scientific Research

There have been more than 2000 published studies carried out on the effects of sulforaphane (that is found in broccoli sprout juice) on various health conditions. We list a few below with research topics that include:

Cancer & CarcinogensIntestinal HealthAutismAlzheimer’s DiseaseParkinson’s DiseaseSkin DisordersAgingEyesAir PollutionDiseases caused by Protein Misfolding

Cancer & Carcinogens

Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens.

Fahey JW, Zhang Y, Talalay P.

Brassica Chemoprotection Laboratory and Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, USA

Proc. Natl. Acad. Sci. USA, Vol. 94, pp. 10367-10372, September 16, 1997.

Sulforaphane inhibits prostate carcinogenesis and pulmonary metastasis in TRAMP mice in association with increased cytotoxicity of natural killer cells.

Singh SV, Warin R, Xiao D, Powolny AA, Stan SD, Arlotti JA, Zeng Y, Hahm ER, Marynowski SW, Bommareddy A, Desai D, Amin S, Parise RA, Beumer JH, Chambers WH. 

Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, USA

Cancer Res. 2009 Mar 1;69(5):2117-25. Epub 2009 Feb 17.

Sulforaphane induces caspase-mediated apoptosis in cultured PC-3 human prostate cancer cells and retards growth of PC-3 xenografts in vivo.

V. Singh, D. Xiao, K. L. Lew, R. Dhir, S. V. Singh

Carcinogenesis, January 1, 2004; 25(1): 83 – 90.

Antimetastatic activity of Sulforaphane

Thejass and Girija Kuttan

Department of Immunology, Amala Cancer Research Centre, Amala Nagar,  India.

Life Sciences Volume 78, Issue 26, 22 May 2006, Pages 3043-3050

Intestinal Health

Oral broccoli sprouts for the treatment of Helicobacter pylori infection: a preliminary report.

[H.pylori infection is associated with stomach ulcers and stomach cancers]

Mark V. Galan, M.D., Arfana A. Kishan, M.D., Ann L. Silverman, M.D.*. 

William Beaumont Hospital, Royal Oak, MI.

The American Journal of Gastroenterology: Volume 98, Issue 9, Supplement 1 , September 2003, Page S57

Dietary sulforaphane-rich broccoli sprouts reduce colonization and attenuate gastritis in Helicobacter pylori-infected mice and humans.

Yanaka A, Fahey JW, Fukumoto A, Nakayama M, Inoue S, Zhang S, Tauchi M, Suzuki H, Hyodo I, Yamamoto M. 

Division of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Tokyo, Japan.

Cancer Prev Res (Phila Pa). 2009 Apr;2(4):353-60

Broccoli ( Brassica oleracea var. italica) sprouts and extracts rich in glucosinolates and isothiocyanates affect cholesterol metabolism and genes involved in lipid homeostasis in hamsters.

Rodríguez-Cantú LN, Gutiérrez-Uribe JA, Arriola-Vucovich J, Díaz-De La Garza RI, Fahey JW, Serna-Saldivar SO. 

Departamento de Biotecnología e Ingeniería de Alimentos, Tecnológico de Monterrey, Mexico.

J Agric Food Chem. 2011 Feb 23;59(4):1095-103. Epub 2011 Jan 21.

Oral sulforaphane increases Phase II antioxidant enzymes in the human upper airway

Riedl MA, Saxon A, Diaz-Sanchez D. 

The Hart and Louis Laboratory, Clinical Immunology and Allergy, Department of Medicine, UCLA David Geffen School of Medicine.

[Ashma] Clin Immunol. 2008 Nov 21.

Sulforaphane Protects Small Intestinal Mucosa From Aspirin/NSAID-Induced Injury by Enhancing Host Defense Systems Against Oxidative Stress and by Inhibiting Mucosal Invasion of Anaerobic Enterobacteria

Yanaka A, Sato J, Ohmori S. 

Hitachi Medical Education and Research Center, Faculty of Medicine, University of Tsukuba Hospital 2-1-1, Jonan-cho, Hitachi-shi, Ibaraki-ken, 317-0077, Japan.

Curr Pharm Des. 2012 Aug 23.

Autism

Sulforaphane treatment of autism spectrum disorder (ASD)

Singh K1234, Susan L. Connors123, Eric A. Macklin35Kirby D. Smith6, Jed W Fahey78, Paul Talalay78, Andrew W. Zimmerman134

1Lurie Center for Autism

2Department of Pediatrics, Massachusetts General Hospital for Children,

3Harvard Medical School

4Department of Pediatrics (Neurology), University of Massachusetts Medical School

5Department of Medicine, Massachusetts General Hospital Biostatistics Enter

6McKusick-Nathans Institute for Genetic Medicine and.

7Department of Pharmacology and Molecular Sciences, Lewis B. and Dorothy Cullman Chemoprotection Center

8The Johns Hopkins University School of Medicine, Baltimore.

PNAS October 28, 2014 vol. 111no. 43 15550-15555

Autism Support Group on Facebook.

We followed what happened when a small group of people with autism drank broccoli sprout juice.   40 parents whose children had autism and who showed the fever response were invited to record what happened when their children drank 30ml Broccoli Sprout Juice per day for 28 days (4 weeks). Health practitioners and CNM Students may contact us for the parents’ comments.

Alzheimer’s Disease

Amelioration of Alzheimer’s disease by neuroprotective effect of sulforaphane in animal model.

Kim HV1, Kim HY, Ehrlich HY, Choi SY, Kim DJ, Kim Y. Amyloid

1Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology, Seoul, Republic of Korea

2013 Mar;20(1):7-12. doi: 10.3109/13506129.2012.751367. Epub 2012 Dec 19.

Parkinson’s Disease

Sulforaphane Protects Cortical Neurons against Endogenous Neurotoxins in a Model of Parkinson’s Disease

Vauzour14, M. Buonfiglio2, G. Corona1, J. Chirafisi1, K. Vafeiadou1, C., Angeloni2, Hrelia2, P. Hrelia3 and J.P.E. Spencer1

1Molecular Nutrition Group, School of Chemistry, Food and Pharmacy, The University of Reading, UK.

2Department of Biochemistry “G. Moruzzi”, University of Bologna, Italy.

3Department of Pharmacology, University of Bologna, Italy.

4Present address: Norwich Medical School, Faculty of Medicine and Health Sciences, University of East Anglia, UK.

Skin Disorders

Isothiocyanates inhibit psoriasis-related proinflammatory factors in human skin.

Yehuda H1, Soroka Y, Zlotkin-Frušić M, Gilhar A, Milner Y, Tamir S.

1Laboratory of Human Health and Nutrition Sciences, MIGAL-Galilee Technology Center, Israel.

Inflamm Res. 2012 Jul;61(7):735-42. doi: 10.1007/s00011-012-0465-3. Epub 2012 Mar 28.

Reprogramming of keratin biosynthesis by sulforaphane restores skin integrity in epidermolysis bullosa simplex.

L. Kerns1, D. DePianto, A. T. Dinkova-Kostova, P. Talalay, P. A. Coulombe

1Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore.

PNAS, September 4, 2007; 104(36): 14460 – 14465.

Aging

Nrf2 activation by sulforaphane restores the age-related decrease of TH1 immunity: Role of dendritic cells: Reverses aging mechanisms in immune system

H.-J. Kim1, B. Barajas, M. Wang, A.E. Nel

1Division of NanoMedicine, Department of Medicine, University of California.

Journal of Allergy and Clinical Immunology (Elsevier) – Published online ahead of print 5 March 2008, doi:10.1016/j.jaci.2008.01.016

Sulforaphane Represses Matrix-Degrading Proteases and Protects Cartilage From Destruction In Vitro and In Vivo 

Rose K. Davidson1, Orla Jupp, Rachel de Ferrars, Colin D. Kay, Kirsty L. Culley, Rosemary Norton, Clare Driscoll, Tonia L. Vincent, Simon T. Donell, Yongping Bao, Ian M. Clark

1University of East Anglia, Norwich, UK.

Arthritis & Rheumatism Vol. 65, No. 12, December 2013, pp 3130–3140 DOI 10.1002/art.38133

Eyes

Molecular mechanisms underlying cochlear [and macular] degeneration in the tubby mouse and the therapeutic effect of sulforaphane.

Kong L, Chen GD, Zhou X, McGinnis JF, Li F, Cao W.

Department of Ophthalmology and Dean A. McGee Eye Institute, University of Oklahoma Health Sciences Center, Oklahoma City, USA.

Neurochem Int. 2009 Mar-Apr;54(3-4):172-9. Epub 2008 Dec 9.

Sulforaphane Induces Thioredoxin through the Antioxidant-Responsive Element and Attenuates Retinal Light Damage in Mice

Tanito M1, H. Masutani, Y.-C. Kim, M. Nishikawa, A. Ohira, and J. Yodoi

1Department of Biological Responses, Institute for Virus Research, Kyoto University, Japan.

Invest. Ophthalmol. Vis. Sci., March 1, 2005; 46(3): 979 – 987.

Air Pollution

Rapid and sustainable detoxication of airborne pollutants by broccoli sprout beverage: results of a randomized clinical trial in China.

Egner PA1, Chen JG2, Zarth AT3, Ng DK4, Wang JB2, Kensler KH1, Jacobson LP4, Muñoz A4, Johnson JL1, Groopman JD1, Fahey JW5Talalay P5Zhu J2, Chen TY2, Qian GS2, Carmella SG3, Hecht SS3, Kensler TW6

1Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205 USA.

2Qidong Liver Cancer Institute, Qidong, Jiangsu, 226200 China.

3Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455 USA.

4Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205 USA.

5Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, MD 21205 USA.

6Department of Pharmacology & Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15261 USA.

Cancer Prev Res (Phila). 2014 Aug;7(8):813-23. doi: 10.1158/1940-6207.CAPR-14-0103. Epub 2014 Jun 9.

Read more about air pollution control in Dangers of Exercise

***Diseases caused by Protein Misfolding***

This is one of THE most important studies ever carried out on sulforaphane because it shows how sulforaphane helps stop a crucial mechanism called protein misfolding that causes many diseases including Type 2 Diabetes, Dementia, Huntingdon’s Disease, Cystic Fibrosis, Sickle Cell Disease and Cataracts.

The amyloid state and its association with protein misfolding diseases.

Knowles TP, Vendruscolo M, Dobson CM

Department of Chemistry, University of Cambridge, UK

Nat Rev Mol Cell Biol. 2014 Jul;15(7):496.

Abstract: The phenomenon of protein aggregation and amyloid formation has become the subject of rapidly increasing research activities across a wide range of scientific disciplines. Such activities have been stimulated by the association of amyloid deposition with a range of debilitating medical disorders, from Alzheimer’s disease to type II diabetes, many of which are major threats to human health and welfare in the modern world. It has become clear, however, that the ability to form the amyloid state is more general than previously imagined, and that its study can provide unique insights into the nature of the functional forms of peptides and proteins, as well as understanding the means by which protein homeostasis can be maintained and protein metastasis avoided.

[This study suggests that this mis-folding of proteins is the genesis of many conditions associated with neurological development or neurological decay. Other studies indicate that sulforaphane can stop or reverse this mis-folding.]

Broccoli Sprout Juice information Broccoli Sprout + Beetroot Juice information

About You

You are our reason for being! We value you over everything because without you we would not exist. So thank you for your interest, your loyalty, your feedback and helping us make Vegus Juices better every year.

Why You Buy Vegus Juices

The reasons you buy our juices are many and if you are new to our site, then we kindly suggest you google sulforaphane and chlorophyll to discover clues as to what makes a huge 90% of you buy again and again.

Where You Live

You live all over the world and it is thanks to you and your referrals and recommending our product that our raw Broccoli sprout juice and Wheatgrass juice are known and bought in over 14 different countries and every year, we have to increase production by double on the previous year to keep up with demand.

Thank you!

Thank you for loyalty and for telling your friends about our wonderful juices.

Learn More About Us:

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About Us

We sell a range of ready-to-drink raw, cold-pressed juice shots.  Our juices are never heated, never frozen and stay fresh for 8 month without storing in the fridge thanks to a special preservation process High Pressure Processing.  HPP uses extreme pressure at cold temperatures to stop bacteria and yet maintains the enzyme activity and nutrients that get destroyed in standard flash heat pasteurisation processes.  Enjoy freshly squeezed, cold-pressed juice everyday with Vegus Juices.

broccoli sprout juice informationBuy broccoli sprout juice

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broccoli sprout + beetroot juice informationBuy broccoli sprout + beetroot juice

Our most popular juice is Broccoli Sprout juice and we are the only company in the world currently making this wonderful juice.  Our Wheatgrass juice is exceptionally but naturally sweet due to the growing conditions we have spent years perfecting. We listened to your feedback and as a result now make a sweeter source of sulforaphane: Broccoli Sprout + Beetroot juice.

Raw food

Raw Food

Vegus Juices are made from cold-pressed juice and are completely raw.  They are never heated and never frozen.  They are preserved using ultra high pressure, known as HPP, to preserve all the nutrients and enzymes so you get to enjoy all the benefits of raw, freshly-squeezed juice whenever you want.

What’s Good about Raw Food?

The nutrients within foods can be more easily digested when the enzymes in those foods are still intact.  In Vegus Juices the important nutrients are sulforaphane in broccoli sprouts juice and chlorophyll in wheatgrass juice.

Why are Enzymes Important?

Enzymes are important because they help break down the food you eat into usable components.  This means that the body does not have to produce these in order to perform the digestive function.

Cooking and heating over 45 degrees Celsius (113 degrees Fahrenheit) denatures (destroys) these enzymes. The heat changes their structure and makes them inactive.  Because most enzymes occurring naturally in food are killed off during processing or cooking, the body lacks the tools to breakdown heated or freeze dried foods properly. This means that instead of being fully digested, the food it is processed in the gut by fermentation with sugars. This leads to indigestion, bloating and constipation. Worst of all the body doesn’t get the food values it needs.  When eating food that still has enzymes present, your food is properly digested so you are able to assimilate all the goodness out of the food your body will feel more satisfied, leaving you less likely crave unhealthy foods.

Vegus Juices are Raw

Vegus Juices are never heated so that all of the enzyme activity is preserved. In fact, tests have shown that the enzyme activity is actually slightly increased by 1-3% after after HPP. This means that it is easier for the body to absorb the important sulforaphane and chlorophyll that are present in our raw juices.  Note that heat-treated dry powdered extracts no longer contain active enzymes.

Enzymes Make a Difference

Have you ever wondered why people who eat raw food look so young and healthy? It’s because they’re eating foods loaded with nutrients and the enzymes in those foods enable them to digest all the nutrients.

Give your body a head start and make sure you include generous portions of salad,  raw vegetables or a raw Vegus Juice with every meal.

What is HPP?

Learn why HPP gives you more sulforaphane.

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our values

Our Values

We at Vegus Juices are a dedicated team driven by the desire to help others.
Our values help shape the juice shots that we make to how we treat you our lovely customers.

We care that you are healthy.

This is fundamentally what drives us to spend hours in rainy Ireland nurturing and loving our sprouts so that our raw juices are full of vibrant living energy for you to enjoy.

We care that you love our juices enough to buy them again.

In fact, 90% of you do buy our raw juice shots again which we are very grateful for.  We love that some of you have been buying our juices for years and many of you tell your friends about us, thank you.

We care about you and why you buy our juices.

You can read some of the reviews about our juices and we’d love to hear your feedback.

We care about the truth.

This is why we encourage you to find out what we know and cannot tell you, by finding out about sulforaphane and chlorophyll.

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